Receptor Activator of Nuclear Factor-κ B Ligand (核因子κ B受体活化因子配体),又名为
TNF-related activation-induced cytokine (TRANCE),TNF相关激活诱导细胞因子;osteoprotegerin ligand (OPGL),
骨保护素配体 osteoclast differentiation factor(ODF ),
破骨细胞分化因子。
Receptor Activator for Nuclear Factor-κ B Ligand (核因子κ B受体活化因子配体),又名为
TNF-related activation-induced cytokine (TRANCE),TNF相关激活诱导细胞因子;osteoprotegerin ligand (OPGL),
骨保护素配体 osteoclast differentiation factor(ODF ),
破骨细胞分化因子。
1
成骨细胞中表达(osteoblast),激活破骨细胞。RANKL过表达,可导致一系列
骨疾病,如
风湿性关节炎,
银屑病性关节炎。