宋淳 ，男，1967年1月出生，现为山东大学药学院教授，博士生导师美国化学学会

1. 药物化学：基于计算机靶标模拟的小分子和大分子药物的设计合成与修饰

2. 药理学研究：药物效应动力学，研究药物对机体的作用，包括药物的作用和效应、作用机制及临床应用等。

药物代谢动力学，研究药物在机体的作用下所发生的变化及其规律，包括药物在体内的吸收、分布、代谢和排泄过程，特别是血药浓度随时间变化的规律、影响药物疗效的因素等。

3. 生物分析学研究：用来测定临床前/临床药物动力学参数的生物分析技术研究、方法验证及标准实验室管理系统。

4. 新药开发：开展针对妇科肿瘤、消化道肿瘤的抗肿瘤原创药物（一类新药）的研发。

1990.9-1993.7 理学硕士 山东大学 化学系

1998.2-2001.11哲学博士 Brigham Young University 有机化学

2009.9-2012.7 哲学博士 天津大学 药学院

1993.7-1995.12 工程师 山东华鲁科技公司

1996.1-1997.9 工程师 山东省科学院

2001.11-2007.5 高级科学家 辉瑞制药

2008.3-2010.5 首席科学家 日东电工

2010.8-2011.4 资深科学家 诺华制药

2011.5-至今教授 山东大学药物制剂与释药系统研究中心

研究生2名，博士生2名

论文

1.Enantioselectiveβ-Boration of Acyclic Enones by a [2.2] Paracyclophane -Based N-HeterocyclicCarbene Copper(I) Catalyst. J. Org. Chem. 2013, 78, 1677−1681.

2.Synthesis of planar chiral[2.2]paracyclophane-based amino thioureas andtheir application in asymmetric aldol reactions of ketones with isatins.Tetrahedron: Asymmetry. 2013,24:1082–1088.

3.Synthesis of novel planar chiral Ag and RhN-heterocyclic carbene complexes derived from [2.2]paracyclophane and theirapplication in ultrasound assisted asymmetric addition reactions oforganoboronic acids to aldehydes. Tetrahedron: Asymmetry .24 (2013) 241–248.

4.Synthesis of newalkoxy/sulfonate-substituted carbene precursors derived from[2.2]paracyclophane and their application in the asymmetric arylation ofaldehydes. Tetrahedron: Asymmetry.2012,23 :1369–1375.

5.Planar Chirality Change in DediazoniationReactions of Paracyclophanes and Mechanistic Implication. Organicletters.2012,14:5436–5439.

6.Asymmetric β-Boration ofr,β-UnsaturatedN-Acyloxazolidinones by [2.2]Paracyclophane-Based Bifunctional Catalys .Organicletters. 2012,14:5780–5783.

7.Benzophenone imine paracyclophane amination.Tetrahedron Lett. 2012, (submitted).

8.Novel effecinet NCH ligands ascross-coupling catalyst and in chiral organocatalysis. Acc.Chem.Res2012,(submitted).

9.Synthesis of cyclophanes with planarandhelical chirelity. J. Org. Chem. 2011, 76, 1953–1956.

10.Synthesis of planar chiral imidazo [1,5-α]pyridinium salts based on [2.2] paracyclophane for asymmetric β-borylation ofenones. Tetrahedron: Asymmetry. 22 (2011) 1055–1062.

11.A new chapter: hematopoietic stem cells aredirect players in immunity. Cell &Bioscience. 2011, 1: 33-37.

12.Synthesis of planar chiral imidazo [1,5-α]pyridinium salts based on [2.2] paracyclophane for asymmetric β-borylation ofenones. Tetrahedron: Asymmetry 2011, 22. 1055.

13.Synthesis of cyclophanes with planarandhelical chirelity. J. Org. Chem. 2011, 76(6), 1953.

14.Planar chiral imidazolium salts based on[2.2]paracyclophane in the asymmetric rhodium-catalyzed 1,2-addition ofarylboronic acids aldehydes. Tetrahedron: Asymmetry. 2010, 21(3), 292.

15.An efficient catalyst system forPd-catalyzed amination of [2.2]paracyclophanyl bromides. J. Org. Chem. 2009,74(17), 6867.

16.Asymmetric allylation of aldehydes withalltrichlorosilane using aza-paracyclophane -oxazoline-N-oxide catalysts.Tetrahedron. Lett. 2006, 47, 8611- 861.

17.Rapid homogeneous-phase sonogashiracoupling reaction using controlled microwave heating in water (invited paper).Green Chemistry, 2005.

18.Palladium catalyzed Suzuki-Miyaura couplingwith aryl chlorides using a bulky phenanthryl N-heterocyclic carbeneligand.Tetrahedron. 2005, 61(31), 7438-7446.

19.Bis-paracyclophane N-heterocycliccarbene-ruthenium catalyzed asymmetric ketone hydrosilylation. TetrahedronLett. 2005, 46(18), 3241-3244.

20.Asymmetric imidazolium catalyzed conjugateaddition. Angew. Chem. Inter. Eng.2003, 42, 5871-5874.

专利

1.PCT/CN2013/077729:Lanthanide labeled peptide and use thereof

2.US2013/882,797 :PEGYLATED CYCLOPAMINEANALOGUE, PREPARATION METHOD AND USES THEREOF

3.PCT/CN2011/000303: PEGYLATED CYCLOPAMINEANALOGUE, PREPARATION METHOD AND USES THEREOF

4.扩增造血干细胞的化合物及其应用

1.21310004011267防治放化疗造成的白细胞减少症的一类新药KEM0977023 临床前研究 山东省科技厅

2.23110371611014新型妇科肿瘤化学治疗体系及其评价系统的建立 教育部创新基金

3.21310005081323新型热休克蛋白90抑制剂的设计合成及抗癌检测 济南市科技局

4.21310005201301 新型大取代基的N-杂环卡宾配体（NHC）配体设计，合成及应用的研究 山东省自然科

2011 泰山学者海外特聘专家