李稼，首都儿科研究所教授，研究员，研究方向为《危重患儿和高原患儿的病理生理研究》。

李稼，教授，研究员，1984年毕业于北京医科大学。

1984-1995在北京安贞医院小儿心脏内科工作，1995至英国伦敦皇家Brompton医院深造。

先后在成人先天性心脏病和先天性心脏病解剖学界世界著名专家DrJane　Summerville 和 Prof Robert Anderson指导下工作。后在英国帝国理工学院获博士学位。博士研究课题为儿童体外循环术后全身氧运输平衡。2002-2013她在加拿大任助教授及副教授，并将呼吸质谱创造性地运用到试验和临床研究中。呼吸质谱研究全身氧运输为该领域提供了金标准数据，发表了大量关于全身氧运输的论文。

危重患儿和高原患儿的病理生理研究

全面地开展科研项目，与院内、院外及国际多个中心合作，取得了丰硕的成果，获得国家自然科学基金一项、首都特色研究基金一项，所级在研课题一项。发表19篇论文，其中sci文章15篇，医学书籍1部。

国家自然科学基金、首都临床特色应用领域与成果推广

1. Zhang G, Holtby H, Cai S, Al Radi O, Li J. Aortic atresia is associated with an inferior postoperative systemic, cerebral and splanchnic oxygen transport status in neonates with hypoplastic left heart syndrome after the Norwood procedure. Eur J Cardiothorac Surg. 2011 39(3):113-21.

2. Yu X, Konstantinov IE, KantochMJ, Rebeyka IM, Li J.Dynamic changes of myocardial oxygen consumption at pacing increased heart rate -- First observation by the continuous measurement of systemic oxygen consumption. ScandCardiovasc J. 2011 Oct;45(5):301-6.

3. ZhangG, SCai, Li J. Hyperglycaemia is negatively associated with systemic and cerebral oxygen transport in neonates after the Norwood procedure. Cardiol Young .2012,22 (1):49-56.

4. Dhillon S, Yu X, Zhang G, Holtby H, Cai S, Li J. The relationship between plasma concentrations of ionized calcium and magnesium with cardiac energetics and systemic oxygen transport in neonates after the Norwood procedure. J ThoracCardiovasc Surg. 2012 Aug;144(2):474-9.

5.Yu X, Larsen B, Urschel S, Cheung PY, Ross DB, Rebeyka I, West L, Li J. The profile of inflammatory and metabolic response in children undergoing heart transplantation.Clin Transplant. 2012 Mar-Apr;26(2)

6. Gill RS, Cheung PY, Yu X, Aklabi MA, Nagendran J, Quinonez LG, Li YQ, Miller J, Ross DB, Rebeyka IM, Li J. β3-adrenoceptor antagonistSR59230A attenuates the imbalance of systemic oxygen transport induced by dopamine in newborn lambs. Clin Med Insights Cardiol. 2012;6:45-51

7. Li J. Systemic oxygen transport derived by using continuous measured oxygen consumption after the Norwood procedure-an interim review. Interact CardiovascThorac Surg. 2012 Jul;15(1):93-101. (Invited review)

8. Yu X, Larsen B, Rutledge J, West L, Ross DB, Rebeyka IM, Buchholz H, Li J.The profile of systemic inflammatory response in children undergoing ventricular assist device support. Interact CardiovascThorac Surg. 2012 Sep;15(3):426-31.

9. J Li. Accurate measurement of oxygen consumption in children undergoing cardiac catheterization. Catheter CardiovascInterv. 2013 Jan 1;81(1):125-32.

10. Zhou Z, Malhotra SP, Yu X, Rutledge J, Rebeyka IM, Ross DB, Rausch C, Gu H, McCrindle B, Lacour-Gayet F, Ivy D, Li J. Moderate altitude is not associated with adverse postoperative outcomes for patients undergoing bidirectional cavopulmonary anastomosis and Fontan operation: A comparative study among Denver, Edmonton, and Toronto. J ThoracCardiovasc Surg. 2013 Nov;146(5):1165-71

11. Cheypesh A, Yu X, Li J. Measurement of systemic oxygen consumption in patients during extracorporeal membrane oxygenation-- Description of a new method and the first clinical observations. Perfusion. 2014;29(1):57-62

12. Li X, Robertson CM, Yu X, Cheypesh A, Dinu IA, Li J. Early postoperative systemic inflammatory response is an important determinant for adverse two-year neurodevelopmental outcomesafter the Norwood procedure. J Thoracic Cardiovascular Surgery. 2014 Jul;148(1):202-6

13. Liyan Zhang, Xiaoyang Yu, AndriyCheypesh, Ivan M Rebeyka, Don Granoski, Gary D. Lopaschuk ,Li J. Plasma fatty acids levels in children during extracorporeal membrane oxygenation support-- A pilot study. J Extra Corpor Technol. 2013;45(4):242

14. ZhuomingXu, Mingjie Zhang, Limin Zhu, Xiaolei Gong, Li J. Elevated plasma B-type natriuretic peptide and C-reactive protein levels in children with restrictive right ventricular physiology following tetralogy of Fallot repair. Congenit Heart Dis. 2014 Nov;9(6):521-8.

15. Qi HY, Ma RY, Jiang LX, Li SP, Mai S, Chen H, Ge M, Wang MY, Liu HN, Cai YH, Xu SY, Li J.Cardiopulmonary changes in healthy children residing at high altitude in china. JACC Cardiovasc Imaging. 2014 Dec;7(12):1281-3.

16. 李稼. 先天性心脏病患儿体外循环术后的神经系统发育异常：术前、术中及术后的影响因素.《中华实用儿科临床杂志》2014;29(18):1368-71

17. SantokhDhillon, Xiaoyang, Gencheng Zhang, Sally Cai, Jia Li. Clinical Hemodynamic Parameters Do Not Accurately Reflect Systemic Oxygen Transport in Neonates after the Norwood Procedure. Congenit Heart Dis. 2015 May;10(3):234-9

18. SantokhDhillon, Xiaoyang, Gencheng Zhang, David B Ross, Jia LiComparison of Profiles of Perioperative Serum C-Reactive Protein Levels in Neonates Undergoing the Norwood Procedure or Arterial Switch Operation.Congenit Heart Dis. 2015 May;10(3):226-33.

19. Qi HY, Ma RY, Jiang LX, Li SP, Mai S, Chen H, Ge M, Wang MY, Liu HN, Cai YH, Xu SY, Li J. Anatomical and hemodynamic evaluations of the heart and pulmonary arterial pressure in healthy children residing at high altitude in China. IJC Heart & Vasculature 2015;7:158–164

20. Xiaohui Li, Xiaoyang Yu, AndriyCheypesh, Jia Li. Non-invasive measurements of energy expenditure and respiratory quotient by respiratory mass spectrometry in children on extracorporeal membrane oxygenation—A pilot study. Artif Organs. 2015 Sep;39(9):815-9.

21. 齐海英,徐素雅,马如雁,蒋丽霞,李淑萍,买抒,陈宏,葛梅,王美英,刘海宁,蔡越红,李稼.中国高原地区与平原地区儿童心脏解剖和功能以及肺循环血液动力学的比较.中华心血管病杂志,2015,43(9):774-781.

22. 韩丁, 刘亚光, 贾清彦, 马骏，罗毅，李稼，欧阳川. 氯胺酮与七氟醚麻醉诱导对先天性心脏病患儿血流动力学的影响. 临床麻醉学杂志, 2015, 31(9): 846-849.

23. 何琛, 韩丁, 刘亚光, 贾清彦, 马骏，罗毅，李稼，欧阳川. 全凭七氟烷吸入麻醉诱导对先天性心脏病患儿血流动力学的影响. 中国医药, 2015, 10(10): 1427-1430.

24. 裴馨, 韩丁, 刘亚光, 贾清彦, 马骏，罗毅，李稼，欧阳川. 不同麻醉诱导方法对小儿室间隔缺损修补术中血流动力学影响的对比研究. 心肺血管病杂志, 2015, 34(10): 759-763.

25. 韩丁, 罗毅, 贾清彦, 汪晓南, 李稼, 欧阳川. 压力记录分析法用于小儿法洛四联症根治术中循环能量效率研究. 心肺血管病杂志, 2016, 35(8): 40-44.

26. Ding Han, Hui Zhang, Bai-Yu Tian, Yan Zhu, Dan Zhang, Yue Li, Yi-Chao Teng, Hong Gu, XuMeng, Yi Luo, De-Ming Zhu and Jia Li. Validation of EGOS-600 Near Infrared Spectroscopy to Measure Cerebral Oxygen Saturation by Comparing to NIRO-200nx In Vitro and In Vivo. J ClinExpCardiolog 2016, 7:5

27. Adaptation of cardioupulmonary system in children at high altitude—The Chinese observations. Scholar’s press.OmniScriptum GmbH & Co. Kg. Germany。 2015（论著）