花强，华东理工大学生物工程学院、生物反应器工程国家重点实验室教授，博士生导师、硕士生导师。

1996–2000 日本九州工业大学生命科学和生物信息学系，工学博士

1993–1996 浙江大学化工系生物化学工程专业，工学硕士

1989–1993 浙江大学化工系生物化学工程专业，工学学士

2008–至今 华东理工大学生物反应器工程国家重点实验室 教授

2007–2008 美国Burnham医学研究所生物信息学和系统生物学部门 研究科学家

2004–2007 美国加州大学圣迭戈分校生物工程系 博士后学者

2001–2004 日本庆应大学先端生命科学研究所 助理教授

1. 细胞代谢工程及系统生物技术开发

2. 细胞基因组规模代谢网络模型的开发及应用研究

3. 微生物细胞工厂构建及代谢工程改造

1.Ting Liu, Linbing Yang, Jun Chen, Fengxian Hu, Liu-Jing Wei,Qiang Hua*. Metabolomic change and pathway profiling reveal enhanced ansamitocin P-3 production inActinosynnema pretiosumwith low organic nitrogen availability in culture medium.Applied Microbiology and Biotechnology, First Online Feb 29, 2020.

2.Feng Liu, Junwen Mao, Ting Lu*,Qiang Hua*. Synthetic, context-dependent microbial consortium of predator and prey.ACS Synthetic Biology, 8(8):1713-1722, 2019.

3.Xin-Kai Zhang, Ming-Yue Nie, Jun Chen, Liu-Jing Wei,Qiang Hua*. Multicopy integrants ofcrtgenes and co-expression of AMP deaminase improve lycopene production inYarrowia lipolytica.Journal of Biotechnology, 289:46-54, 2019.

4.Qi Gao, Xuan Cao, Yu-Ying Huang, Jing-Lin Yang, Jun Chen, Liu-Jing Wei*,Qiang Hua*. Overproduction of fatty acid ethyl esters by the oleaginous yeastYarrowia lipolyticathrough metabolic engineering and process optimization.ACS Synthetic Biology, 7(5):1371-1380, 2018.

5.Deqing Gu, Xingxing Jian, Cheng Zhang,Qiang Hua*. Reframed genome-scale metabolic model to facilitate genetic design and integration with expression data.IEEE/ACM Transactions on Computational Biology and Bioinformatics, 14(6):1410-1418, 2017.

6.Xuan Cao, Liu-Jing Wei, Jia-Yu Lin,Qiang Hua*. Enhancing linalool production by engineering oleaginous yeastYarrowia lipolytica.Bioresource Technology, 245(B):1641-1644, 2017.

7.Xingxing Jian, Ningchuan Li, Qian Chen,Qiang Hua*. Model-guided identification of novel gene amplification targets for improving succinate production inEscherichia coliNZN111.Integrative Biology, 9:830-835, 2017.

8.Chen Zhao, Qi Gao, Jun Chen, Liujing Wei, Tadayuki Imanaka,Qiang Hua*. Metabolomic changes and metabolic responses to expression of heterologous biosynthetic genes for lycopene production inYarrowia lipolytica.Journal of Biotechnology, 251(3):174-185, 2017.

9.Xuan Cao, Yu-Bei Lv, Jun Chen, Liu-Jing Wei*,Qiang Hua*. Metabolic engineering of oleaginous yeastYarrowia lipolyticafor limonene overproduction.Biotechnology for Biofuels, 9:214, 2016.

10.Xingxing Jian, Shengguo Zhou, Cheng Zhang,Qiang Hua*. In silico identification of gene amplification targets based on analysis of production and growth coupling.Biosystems, 145:1-8, 2016.

11.Yuxiang Fan, Fengxian Hu, Liujing Wei, Linquan Bai,Qiang Hua*. Effects of modulation of pentose-phosphate pathway on biosynthesis of ansamitocins inActinosynnema pretiosum.Journal of Biotechnology, 230:3-10, 2016.

12.Cheng Zhang, Sunjae Lee, Adil Mardinoglu*,Qiang Hua*. Investigating the combinatory effects of biological networks on gene co-expression.Frontiers in Physiology, 7:160, 2016.

13.Deqing Gu, Cheng Zhang, Shengguo Zhou, Liujing Wei,Qiang Hua*. IdealKnock: A framework for efficiently identifying knockout strategies leading to targeted overproduction.Computational Biology and Chemistry, 61:229-237, 2016.

14.Yuxiang Fan, Mengjiang Zhao, Liujing Wei, Fengxian Hu, Tadayuki Imanak, Linquan Bai,Qiang Hua*. Enhancement of UDPG synthetic pathway improves ansamitocin production inActinosynnema pretiosum.Applied Microbiology and Biotechnology, 100:2651-2662, 2016.

15.Cheng Zhang,Qiang Hua*. Applications of genome-scale metabolic models in biotechnology and systems medicine.Frontiers in Physiology, 6:413, 2016.