陈增萍
湖南大学化学化工学院教授、博士生导师
陈增萍,男,毕业于湖南大学,博士,湖南大学化学化工学院教授、博士生导师
人物经历
教育经历
2002.10-2008.11 英国钮卡斯尔大学化工与先进材料学院,博士后。
1998.09-2001.05 湖南大学化学化工学院,理学博士;
1995.09-1998.06 湖南大学化学化工学院,理学硕士;
1991.09-1995.06 湖南大学化学化工学院,理学学士;
工作经历
2008.12- 现在 湖南大学化学化工学院,教授、博士生导师。
2001.06- 2002.09 湖南大学化学化工学院,讲师。
学术兼职
英国斯特斯克莱德大学(University of Strathclyde)纯粹与应用化学系荣誉教师
研究领域
目前主要从事复杂体系波谱定量分析理论和应用方面的研究,研究内容主要包括:复杂生物体系质谱定量分析技术、表面增强拉曼光谱定量分析技术、荧光化学生物传感技术、化学计量学理论和方法等。所获得的研究成果可望为临床疾病诊断、生物医学研究、食品和药品安全检测、以及环境监测和保护等领域提供重要的工具。
科研项目
1. 国家自然科学基金,基于分子探针技术的化学计量学定量分析理论及其应用研究,2018.1-2021.12。
2. 国家自然科学基金非均相体系荧光化学生物传感技术中的化学计量学理论及应用研究,2015.1-2018.12。
3. 国家自然科学基金,具有普适性的表面增强拉曼光谱定量分析技术的研究,2013.1-2016.12。
4. 国家自然科学基金,复杂多相体系拉曼光谱定量分析的化学计量学方法研究,2011.1-2013.12。
5. 科技部重大科学仪器设备开发专项子任务,SHINERS粒子模型设计与理论研究,2011.9-2015.8。
6. 湖南省自然科学基金,复杂非均相体系荧光化学生物传感定量分析理论及应用研究,2016.1-2017.12。
7. 教育部博士点基金(博导类),复杂非均相体系原位光谱定量分析基础理论研究,2014.1-2016.12。
8. 教育部新世纪人才计划,化学计量学,2013.1-2014.12。
学术成果
科研论文
Shi, C.X.; Chen, Z.P.*; Chen, Y.; Liu, Q.; Yu, R.Q. Quantification of dopamine in biological samples by surface-enhanced Raman spectroscopy: comparison of different calibration models, Chemometrics and Intelligent Laboratory Systems, 2017, 169, 87-93
Zuo, Q.; Xiong, S.; Chen, Z.P.*; Chen, Y.; Yu, R.Q. A novel calibration strategy based on background correction for quantitative circular dichroism spectroscopy, Talanta, 2017, 174, 320-324
Kong, J.J.; Chen, Z.P.*; Chen, Y.; Yan, X.F.; Yu, R.Q. Direct DNA quantification in cell lysates by fluorometric method in combination with an advanced chemometric model, Chemometrics and Intelligent Laboratory Systems, 2016, 151, 9-14
Hu, Y.L.; Chen, Z.P.*; Chen, Y.; Shi, C.X.; Yu, R.Q. Generalized multiple internal standard method for quantitative liquid chromatography mass spectrometry, Journal of Chromatography A, 2016, 1445, 112-117
Yan, X.F.; Chen, Z.P.*; Cui, Y.Y.; Hu, Y.L.; Yu, R.Q. Quantitative generalized ratiometric fluorescence spectroscopy for turbid media based on probe encapsulated by biologically localized embedding, Analytica Chimica Acta, 2016, 921, 38-45
Chen, Y.; Chen, Z.P.*; Zuo, Q.; Shi, C.X.; Yu, R.Q. Surface-enhanced Raman spectroscopy based on conical holed enhancing substrates, Analytica Chimica Acta, 2015, 887, 45-50
Yan, X.F.; Chen, Z.P.*; Kong, J.J.; Hu, Y.L.; Chen, Y.; Yu, R.Q. Determination of free Mg2+ in turbid samples with the coexistence of interfering Ca2+ using extended quantitative fluorescence model, Chemometrics and Intelligent Laboratory Systems, 2015, 147, 41-46
Shi, C.X.; Chen, Z.P.*; Chen, Y.; Yu, R.Q. Quantitative analysis of hormones in cosmetics by LC-MS/MS combined with an advanced calibration model, Analytical Methods, 2015, 7, 6804-6809
Long, S.Y.; Chen, Z.P.*; Chen, Y.; Yu, R.Q. Quantitative detection of captopril in tablet and blood plasma samples by the combination of surface-enhanced Raman spectroscopy with multiplicative effects model, Journal of Raman Spectroscopy, 2015, 46, 605-609
Chen, Y.; Chen, Z.P.*; Jin, J.W.; Yu, R.Q. Quantitative determination of ametryn in river water using surface-enhanced Raman spectroscopy coupled with an advanced chemometric model, Chemometrics and Intelligent Laboratory Systems, 2015, 142, 166-171
Chen, Y.; Chen, Z.P.*; Long, S.Y.; Yu, R.Q. Generalized ratiometric indicator based surface-enhanced Raman spectroscopy for the detection of Cd2+ in environmental water samples, Analytical Chemistry, 2014, 86, 12236-12242
Du, H.L.; Chen, Z.P.*; Song, M.; Chen, Y.; Yu, R.Q. Novel calibration model maintenance strategy for solving the signal instability in quantitative liquid chromatography–mass spectrometry, Journal of Chromatography A, 2014, 1338, 44-50
Jin, J.W.; Chen, Z.P.*; Song, J.; Xia, T.H.; Yu, R.Q. Determination of glucose in plasma by dry film-based near infrared spectroscopy: correcting the thickness variations of dry films without applying an internal standard, Chemometrics and Intelligent Laboratory Systems, 2014, 135, 63-69
Song, M.; Chen, Z.P.*; Chen, Y.; Jin, J.W. Multiplicative effects model with internal standard in mobile phase for quantitative liquid chromatography-mass spectrometry, Talanta, 2014, 125, 347-351.
Xia, T.H.; Chen, Z.P.*; Chen, Y.; Jin J.W.; Yu, R.Q. Improving the quantitative accuracy of surface enhanced Raman spectroscopy by the combination of microfluidics with a multiplicative effects model, Analytical Methods, 2014, 6, 2363-2370
Song, J.; Chen, Z.P.*; Jin, J.W.; Chen, Y.; Yu, R.Q. Quantitative surface-enhanced Raman spectroscopy based on the combination of magnetic nanoparticles with an advanced chemometric model, Chemometrics and Intelligent Laboratory Systems, 2014, 135, 31-36
Chen, Y.; Chen, Z.P.*; Yang J.; Jin, J.W.; Zhang, J.; Yu, R.Q. Quantitative fluorescence spectroscopy in turbid media: a practical solution to the problem of scattering and absorption, Analytical Chemistry, 2013, 85, 2015-2020
Yang, J.; Chen, Z.P.*; Zhang, J.; Jin, J.W.; Chen, Y. Quantitative Raman spectrometry: the accurate determination of analytes in solution phase of turbid media, Chemometrics and Intelligent Laboratory Systems, 2013, 126, 6-10
Zhang, J.; Liu S.Z.; Yang, J.; Song, M.; Song, J.; Du, H.L.; Chen, Z.P.* Quantitative spectroscopic analysis of heterogeneous systems: chemometric methods for the correction of multiplicative light scattering effects, Review in Analytical Chemistry , 2013, 32(2), 113-125
Chen, Z.P*; Li, L.M.; Jin, J.W.; Nordon, A.; Littlejohn, D.; Yang, J.; Zhang, J.; Yu, R.Q. Quantitative analysis of powder mixtures by Raman spectrometry: the influence of particle size and its correction, Analytical Chemistry, 2012, 84, 4088-4094
Jin, J.W.; Chen, Z.P.*; Li, L.M.; Steponavicius, R.; Thennadil, S.N.; Yang, J.; Yu, R.Q. Quantitative spectroscopic analysis of heterogeneous mixtures: the correction of multiplicative effects caused by variations in physical properties of samples, Analytical Chemistry, 2012, 84, 320-326
Chen Z.P.*; Zhong L.J.; Nordon A.; Littlejohn D.; Holden M.; Fazenda M.; Harvey L.; McNeil B.; O’Kennedy R. Calibration of multiplexed fibre-optic spectroscopy, Analytical Chemistry, 2011, 83, 2655-2659
Chen Z.P.*; Li L.M.; Yu R.Q.; Littlejohn D.; Nordon A.; Morris J.; Dann A.S.; Jeffkins P.A.; Richardson M.D.; Stimpson S.L. Systematic prediction error correction: a novel strategy for maintaining the predictive abilities of multivariate calibration models, Analyst, 2011, 136, 98-106
Chen Z.P.; Lovett D.; Morris J. Process analytical technologies and real time process control a review of some spectroscopic issues and challenges, Journal Process Control, 2011, 21, 1467-1482
Du W.; Chen Z.P.*; Zhong L.J.; Wang S.X.; Yu R.Q.; Nordon A.; Littlejohn D.; Holden M. Maintaining the predictive abilities of multivariate calibration models by spectral space transformation, Analytica Chimica Acta, 2011, 690, 64-70
Chen, Z.P.*; Morris, J. Borissova, A.; Khan, S.; Mahmud, T.; Penchev, R.; Roberts, K. On-line monitoring of batch cooling crystallisation of organic compounds using ATR-FTIR spectroscopy coupled with an advanced chemometric calibration method, Chemometrics and Intelligent Laboratory Systems, 2009, 96, 49-58
Chen, Z.P.; Morris, J. Process analytical technology and compensating for nonlinear effects in process spectroscopic data for improved process monitoring and control, Biotechnology Journal, 2009, 4, 610-619
Chen, Z.P.*; Fevotte, G.; Caillet, A.; Littlejohn, D.; Morris, J. Advanced calibration strategy for in-situ quantitative monitoring of phase transition processes in suspensions using FT-Raman spectroscopy, Analytical Chemistry, 2008, 80, 6658-6665
Chen, Z.P.*; Morris, J. Improving the linearity of spectroscopic data subjected to fluctuations in external variables by the extended loading space standardization, Analyst, 2008, 133, 914-922
Chen, Z.P.; Lovett, D.; Morris, J. Process analytical technologies (PAT)-the impact for process systems engineering, Computer Aided Chemical Engineering, 2008, 25, 967-972
Chen, Z.P.; Morris, J.; Martin, E. Extracting chemical information from spectral data with multiplicative light scattering effects by optical path-length estimation and correction, Analytical Chemistry, 2006, 78, 7674-7681
Chen, Z.P.; Morris, J.; Martin, E. Correction of temperature-induced spectral variations by loading space standardization, Analytical Chemistry, 2005, 77, 1376-1384
Chen, Z.P.; Morris, J.; Martin, E.; Hammond, R.B.; Lai, X.J.; Ma, C.Y.; Purba, E.; Roberts, K.J.; Bytheway, R. Enhancing the signal-to-noise ratio of X-ray diffraction profiles by smoothed principal component analysis, Analytical Chemistry, 2005, 77, 6563-6570
Chen, Z.P.; Morris, J.; Martin, E.; Yu, R.Q.; Liang, Y.Z.; Gong, F. Recursive evolving spectral projection for revealing the concentration windows of overlapping peaks in two-way chromatographic experiments, Chemometrics and Intelligent Laboratory Systems, 2004, 72, 9-19
Chen, Z.P.; Yu, R.Q. Mitigating model deficiency in three-way data analysis by the combination of background constraining and iterative correcting techniques, Analytica Chimica Acta, 2003, 487, 171-180
Chen, Z.P.; Wu, H.L.; Li, Y.; Yu, R.Q. On self-weighted alternating trilinear decomposition algorithm-the property of being insensitive to the excess factors used in calculation, Journal of Chemometrics, 2001, 15, 427-438
Chen, Z.P.; Li, Y.; Yu, R.Q. Pseudo alternating least squares algorithm for trilinear decomposition, Journal of Chemometrics, 2001, 15, 149-167
Chen, Z.P.; Liu, Z. Cao, Y. Z.; Yu, R.Q. Efficient way to estimate the optimum number of factors for trilinear decomposition, Analytica Chimica Acta, 2001, 444, 295-307
Chen, Z.P.; Wu, H.L.; Jiang, J.H.; Li, Y.; Yu, R.Q. A novel trilinear decomposition algorithm for second orders linear calibration, Chemometrics and Intelligent Laboratory Systems, 2000, 52, 75-86
Chen, Z.P.; Wu, H.L.; Li, Y.; Yu, R.Q. Novel constrained PARAFAC algorithm for second order linear calibration, Analytica Chimica Acta, 2000, 423, 187-196
Chen, Z.P.; Jiang, J.H.; Li, Y.; Liang, Y.Z.; Yu, R.Q. Fuzzy linear discriminant analysis for chemical data sets, Chemometrics and Intelligent Laboratory Systems, 1999, 45, 295-302
Chen, Z.P.; Jiang, J.H.; Li, Y.; Yu, R.Q. Non-linear mapping using real-valued genetic algorithm, Chemometrics and Intelligent Laboratory Systems, 1999, 45, 409-418
Chen, Z.P.; Liang, Y.Z.; Jiang, J.H.; Li, Y.; Qian, J.Y.; Yu, R.Q. Determination of the number of components in mixtures using a new approach incorporating chemical information, Journal of Chemometrics, 1999, 13, 15-30
Chen, Z.P.; Jiang, J.H.; Li, Y.; Shen, H.L.; Liang, Y.Z.; Yu, R.Q. Smoothed window factor analysis, Analytica Chimica Acta, 1999, 381, 233-246
发明专利
陈增萍、俞汝勤. 用于维护复杂体系光谱校正模型预测能力的方法, 中国发明专利, 专利号:ZL201210243634.0(2012.05.23)
陈增萍、金竞文、俞汝勤. 用于复杂非均相混合物体系的准确光谱定量分析方法,中国发明专利, 专利号:ZL201110280639.6(2013.09.04)
陈增萍、李丽梅、金竞文. 一种粉末混合物的拉曼光谱准确定量分析方法,中国发明专利, 专利号:ZL201110409685.1(2013.11.20)
陈增萍、金竞文、俞汝勤. 具有普适性的表面增强拉曼光谱定量分析技术,中国发明专利, 专利号:ZL201210243634.0(2014.04.16)
陈增萍,陈瑶,田中群. 一种环境水体样本中镉离子含量的定量分析方法,专利号:ZL201410439838.0(2016.06.08)
陈增萍,陈瑶,田中群. 一种增强SERS信号的方法及其应用,中国发明专利, 专利号:ZL201510002031.5(2017.08.04)
奖励荣誉
曾获湖南省2002自然科学技术一等奖
参考资料
陈增萍 .湖南大学化学化工学院.
最新修订时间:2024-06-24 11:44
目录
概述
人物经历
参考资料